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Antimicrobial use in food animal production: situation analysis and contributing factors

Ziping WU

《农业科学与工程前沿（英文）》 2018年 第5卷 第3期   页码 301-311 doi: 10.15302/J-FASE-2018207

摘要：

By measuring the quantity and ways in which antimicrobials are used, and reviewing different technical and socioeconomic factors influencing antimicrobial use at farm level, this study discusses the main knowledge gaps in antimicrobial use in food animal production and provides recommendations for future research and policy development. The review reveals that antimicrobial use in food animals exhibit strong regional and species differences, and there are still large information gaps concerning the current state of antimicrobial use. Factors associated with animal health (including antimicrobial resistance), animal health improvement, economic costs and benefits relevant to animal diseases, and potential technological alternatives or alternative systems all have an impact on antimicrobial use on the farm. There is a clear need to resolve the data gap by monitoring antimicrobial use and developing an analytical framework to better understand farmer behaviors under different technical, economic and environmental circumstances.

关键词： antimicrobial use     drivers for antimicrobial use     food animal production    

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Discovery of novel ursolic acid derivatives as effective antimicrobial agents through a ROS-mediated

《化学科学与工程前沿（英文）》 2023年 第17卷 第12期   页码 2101-2113 doi: 10.1007/s11705-023-2361-5

摘要： In response to the reduction of food production and economic losses caused by plant bacterial diseases, it is necessary to develop new, efficient, and green pesticides. Natural products are rich and sustainable source for the development of new pesticides due to their low toxicity, easy degradation, and eco-friendliness. In this study, we prepared three series of ursolic acid derivatives and assessed their antibacterial ability. Most target compounds exhibited outstanding antibacterial activities. Among them, the relative optimal EC50 values of Xanthomonas oryzae pv. oryzae and Xanthomonas axonopodis pv. citri were 2.23 (A17) and 1.39 (A16) μg·mL–1, respectively. The antimicrobial mechanism showed that compound A17 induced an excessive accumulation and production of reactive oxygen species in bacteria and damaged the cell membrane integrity to kill bacteria. More interestingly, the addition of low concentrations of exogenous hydrogen peroxide enhanced the antibacterial efficacy of compound A17 against Xanthomonas oryzae pv. oryzae. These entertaining results suggested that compound A17 induced an apparent apoptotic behavior in the tested bacteria. Overall, we developed the promising antimicrobial agents that destroyed the redox system of phytopathogenic bacteria, further demonstrating the unprecedented potential of ursolic acid for agricultural applications.

关键词： ursolic acid     antibacterial activities     reactive oxygen species     apoptosis    

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of copper nanoparticles on multiwalled carbon nanotubes modified with poly (acrylic acid) and their antimicrobial

Li SHENG,Shuhang HUANG,Minghao SUI,Lingdian ZHANG,Lei SHE,Yong CHEN

《环境科学与工程前沿（英文）》 2015年 第9卷 第4期   页码 625-633 doi: 10.1007/s11783-014-0711-8

摘要： A novel hybrid material, Cu-PAA/MWCNTs (copper nanoparticles deposited multiwalled carbon nanotubes with poly (acrylic acid) as dispersant, was prepared and expected to obtain a more effective and well-dispersed disinfection material for water treatment. X-ray energy dispersive spectroscopy (EDS), transmission electron microscopy (TEM), the X-ray fluorescence (XRF), X-ray photoelectron spectra (XPS), Fourier transform infrared spectra (FT-IR), Raman spectroscopy, and thermal gravimetric analyzer (TGA) were used to characterize the Cu-PAA/MWCNTs. ( ) was employed as the target bacteria. The cell viability determination and fluorescence imaging results demonstrated that Cu-PAA/MWCNTs possessed strong antimicrobial ability on . The deposited Cu was suggested to play an important role in the antimicrobial action of Cu-PAA/MWCNTs.

关键词： multiwalled carbon nanotubes     copper nanoparticles     antimicrobial activity     Escherichia coli (E. coil)    

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Review on drivers, trends and emerging issues of the food wastage in China

Lin MA,Wei QIN,Tara GARNETT,Fusuo ZHANG

《农业科学与工程前沿（英文）》 2015年 第2卷 第2期   页码 159-167 doi: 10.15302/J-FASE-2015066

摘要： China has successfully achieved food self-sufficiency over the past 50 years, however, with large inputs and losses. To meet the challenge of feeding a growing population with limited resources, many studies have explored options for improving productivity and efficiency of the food production. However, there have been few studies into the potential of reducing food loss along the whole food production-consumption chain. Here we review the literature on food waste in China. We briefly analyze (1) the drivers that influence levels of food waste in the food chain, (2) examine trends in the volumes and types of food wasted at different stages in the food chain, (3) assess the environmental and resource consequences of food waste in the food chain, and (4) evaluate the policy and stakeholder responses to the emerging challenges. It is concluded that reducing food loss and meeting food security in China requires a coherent institutional structure that promotes the synergistic outcomes of research, policy and education. Suggested key actions include (1) improving machinery and facility for sowing, harvesting, transportation and storage, which can reduce food loss by up to 50%, and (2) improving food waste recycling management, based on coupled food production and consumption systems.

关键词： food security     food chain     food wastes and losses     environmental impacts    

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Microwave-assisted synthesis and antimicrobial activities of 2-aryl-3-(naphthalene-1 or 2-yl)-1,3-thiazolidin

Hua CHEN, Yanan LI, Jie BAI, Lian ZHAO, Xiangguo YUAN, Xiaoliu LI, Keqiang CAO

《化学科学与工程前沿（英文）》 2009年 第3卷 第2期   页码 186-191 doi: 10.1007/s11705-009-0004-0

摘要： 2-aryl-3-(naphthalene-1 or 2-yl)-1,3-thiazolidin-4-ones and were synthesized in 41%-67% yield by using microwave-assisted one-pot protocol. The structures of the new compounds , , , , , , and - were confirmed by IR, NMR, MS, and elemental analysis. The antimicrobial activities of the compounds against pv. lachrymans (Smith et Bryan) Young, Dye & Wilkie, Pers., and Blum. were examined. Some of the compounds showed good antifungical activity against Blum.

关键词： microwave-assisted synthesis     naphthyl     thiazolidin-4-one     antimicrobial    

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Antimicrobial activity of topical agents against Propionibacterium acnes: an in vitro study of clinical

null

《医学前沿（英文）》 2016年 第10卷 第4期   页码 517-521 doi: 10.1007/s11684-016-0480-9

摘要：

This study aimed to compare the antimicrobial activities of topical agents against Propionibacterium acnes isolated from patients admitted to a hospital in Shanghai, China. The minimal inhibitory concentrations of the cultured P. acnes were determined in accordance with the Clinical and Laboratory Standards Institute. Susceptibilities to clindamycin and erythromycin were compared in terms of gender, age, disease duration, previous treatment, and disease severity. A total of 69 P. acnes strains were isolated from 98 patients (70.41%). The susceptibility to triple antibiotic ointment (neomycin/bacitracin/polymyxin B) and bacitracin was 100%. The susceptibility to fusidic acid was 92.7%. The resistance rates to neomycin sulfate, erythromycin, and clindamycin were 11.7%, 49.3%, and 33.4%, respectively. The high resistance rate to clindamycin and erythromycin was significantly affected by gender, previous treatment, and disease severity rather than by age and disease duration. Topical antibiotics should not be used separately for long-term therapy to avoid multiresistance. The use of topical antibiotics should be determined by clinicians on the basis of clinical conditions.

关键词： antimicrobial susceptibility/resistance     Propionibacterium acnes     topical antibiotics     in vitro study    

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Decomposing drivers of transportation energy consumption and carbon dioxide emissions for the Philippines

Neil Stephen LOPEZ, Anthony S.F. CHIU, Jose Bienvenido Manuel BIONA

《能源前沿（英文）》 2018年 第12卷 第3期   页码 389-399 doi: 10.1007/s11708-018-0578-7

摘要：

Global CO2 emissions increased by 57.9% from 1990 to 2014, of which 21% is known to be from the transportation sector. In line with policy development, driving forces to energy consumption and emissions may be determined using decomposition analysis techniques. However, the detail of information required to perform such studies for the transportation sector in developing countries can be challenging. An attempt was made in this study to formulate a decomposition analysis framework considering data availability and limitation in developing countries. Furthermore, a suggestion of adjusting transport activity data using average oil price was proposed. An illustrative case study in the Philippines revealed that the most significant driver was transport activity, followed by energy intensity, and then population growth, which was both similar and contrary to all previous studies performed in developed and rapidly urbanizing countries, which pointed out to transport activity as the primary contributing force. For the Philippines, transport activity was an inhibiting force, whereas energy intensity was the primary contributing factor. The difference could be explained by the differences in mode shares and quality of life between countries. Looking at private vehicle ownership data, it is observed that growth rates are higher in the rural, than in the urban centers. Deriving from the findings, developing a comprehensive public transport plan is recommend for future growth areas, expansion and modernization of public transport services in the city, and strategic deployment of transport policies.

关键词： transportation     LMDI     decomposition     developing country     emissions    

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What drivers will influence biomass allocation

Jinguang HU, William James CADHAM, Susan van DYK, Jack N. SADDLER

《农业科学与工程前沿（英文）》 2017年 第4卷 第4期   页码 473-481 doi: 10.15302/J-FASE-2017168

摘要： Potential competition for biomass for current and future bioenergy/biofuel uses in Brazil, Denmark, Sweden and the USA were compared. In each of these countries, bioenergy and biofuels are already important in their energy mix. However, there is limited competition for biomass between bioenergy (heat/power/residential/industrial) and transportation biofuel applications. This situation is likely to continue until advanced biofuel technology becomes much more commercially established. In each of these countries, biomass is predominantly used to produce bioenergy, even in those regions where biofuels are significant component of their transportation sector (Brazil, Sweden and USA). The vast majority of biofuel production continues to be based on sugar, starch and oil rich feedstocks, while bioenergyis produced almost exclusively from forest biomass with agricultural biomass having a small, but increasing, secondary role. Current and proposed commercial scale biomass-to-ethanol facilities almost exclusively use agriculture derived residues (corn stover/wheat straw/sugarcane bagasse). Competition for biomass feedstocks for bioenergy/biofuel applications, is most likely to occur for agricultural biomass with coproduct lignin and other residues used to concomitantly produce heat and electricity on site at biofuel production facilities.

关键词： bioenergy     biofuel     biomass     renewable energy policy    

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越南广平和顺化两省猪场分离副猪嗜血杆菌的抗生素耐药表型和耐药基因之间的相关性研究 Article

Chao Nguyen Van, 张丽君, Tam Vu Thi Thanh, Hung Pham Hoang Son, Tuan Tran Ngoc, 黄琦, 周锐

《工程（英文）》 2020年 第6卷 第1期   页码 40-48 doi: 10.1016/j.eng.2019.10.014

摘要：

副猪嗜血杆菌是一种对全球养猪业造成重大经济损失的病原菌。副猪嗜血杆菌防控失败的原因之一是细菌耐药性不断加重。越南拥有亚洲排名第二的生猪产量，但是缺乏针对副猪嗜血杆菌耐药性的相关研究和数据。本研究的目的是调查越南副猪嗜血杆菌的耐药性，并分析耐药性和耐药性基因之间的关系。本研究所使用的副猪嗜血杆菌分离菌株来自我们之前研究中从越南广平省和顺化省猪场分离到的菌株。本研究分别利用肉汤微稀释法和聚合酶链反应（PCR）法检测了这些菌株对25种抗生素的耐药性及相关耐药基因的存在情况。结果显示，这些分离株对甲氧苄啶/磺胺甲恶唑的耐药率达高到94.6%，其次是黏菌素、氯霉素、庆大霉素、青霉素、林可霉素和阿莫西林。这些菌株中相关联耐药基因的检出率分别为blaTEM-1 94.6%、int 76.8%、gyrA 58.9%以及rmtD 50.0%。头孢呋辛、氯霉素和妥布霉素的耐药性表型分别与耐药基因blaROB-1 [优势比（OR） = 26.3, 95% 置信区间（CI）2.7~255.7, p = 0.002]、catl (OR = 25.1, 95% CI 2.4~258.9, p = 0.004)以及strB (OR = 23.5, 95% CI 2.6~212.6, p = 0.001)呈显著正相关。本研究首次揭示了越南中部地区副猪嗜血杆菌的耐药性情况，有助于该疾病的临床控制，能够为降低越南中部的养猪业中该菌的耐药性以及为相关政策制定和临床用药提供指导。

关键词： 副猪嗜血杆菌，抗药性，耐药基因，越南    

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Moving policy and regulation forward for single-use plastic alternatives

《环境科学与工程前沿（英文）》 2021年 第15卷 第3期 doi: 10.1007/s11783-021-1423-5

摘要： Single-use plastics are often used once or cannot be reused for extended periods. They are widely consumed with the rapid development of social economy. The waste generated by single-use plastics threatens ecosystem health by entering the environment and ultimately restricts sustainable human development. The innovation of sustainable and environmentally friendly single-use plastic alternative materials and the joint participation of governments, enterprises and the public are promising technologies and management approaches that can solve the problem of single-use plastics wastes. The development of single-use plastic alternative products can be promoted fundamentally only by improving relevant legislation and standards, providing differentiated industrial policies, encouraging scientific and technological innovation and expanding public participation.

关键词： Single-use plastic alternatives     Policy     Regulation     Sustainable development    

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吖啶– 核定位序列偶联构建的高活性抗菌肽 Artical

Wei Zhang,Xiaoli Yang,Jingjing Song,Xin Zheng,Jianbo Chen,Panpan Ma,Bangzhi Zhang,Rui Wang

《工程（英文）》 2015年 第1卷 第4期   页码 500-505 doi: 10.15302/J-ENG-2015106

摘要：

多重耐药菌的出现迫切需要发现具有新作用机制的抗生素。在本研究中，笔者将疏水的吖啶分子连接到核定位序列 (NLS) 的N末端合成了一种新型的抗菌药物Acr3-NLS。为了进 一步提高该试剂的抗菌活性，笔者将两个单体Acr3-NLS分子通过二硫键连接合成了二聚体(Acr3-NLS)2。结果显示，与NLS相比，Acr3-NLS，特别是(Acr3-NLS)2，对革兰阴性菌和革兰阳性菌表现出显著的抗菌活性。随后，其作用机制的研究表明，Acr3-NLS 和(Acr3-NLS)2 可通过细胞膜破坏方式和DNA 结合方式杀死细菌。作用于细胞膜和细胞内DNA的双靶点抑杀机制可以降低细菌对Acr3-NLS 和(Acr3-NLS)2 产生耐药性的风险。总之， 本研究提供了一种新的策略，可用于设计具有双重作用机制的高效抗菌药物。

关键词： 吖啶     核定位序列     共轭连接     抗菌活性     作用机制    

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细菌耐药性威胁人类健康 Editorial

沈建忠, Timothy R. Walsh

《工程（英文）》 2022年 第15卷 第8期   页码 1-2 doi: 10.1016/j.eng.2022.06.003

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Nudging sustainable consumption of residential energy use: A behavioral economics perspective

《工程管理前沿（英文）》   页码 540-545 doi: 10.1007/s42524-023-0264-2

摘要： Nudging sustainable consumption of residential energy use: A behavioral economics perspective

关键词： consumption energy use    

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Drivers and barriers to engage enterprises in environmental management initiatives in Suzhou Industrial

Bing ZHANG, Jun BI, Beibei LIU

《环境科学与工程前沿（英文）》 2009年 第3卷 第2期   页码 210-220 doi: 10.1007/s11783-009-0014-7

摘要： Small- and medium-sized enterprises (SMEs) play an important role in sustainable development not only for their significant contribution to China’s economy, but also for their big share of total discharged pollutants. Therefore, this research takes the enterprises in Suzhou Industrial Park, China as the case study to investigate the environmental management practices of SMEs, and identify drivers and barriers to engaging businesses in environmental management initiatives. It is shown that, as in other countries, SMEs are less active in adopting environmental management initiatives than larger companies. Legislation remains the key driver to engage SMEs in environmental management initiatives. Based on the analysis, policy recommendations are also presented.

关键词： small- and medium-sized enterprises (SMEs)     environmental management initiative     Suzhou industrial park    

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Approaches to achieve high grain yield and high resource use efficiency in rice

Jianchang YANG

《农业科学与工程前沿（英文）》 2015年 第2卷 第2期   页码 115-123 doi: 10.15302/J-FASE-2015055

摘要： This article discusses approaches to simultaneously increase grain yield and resource use efficiency in rice. Breeding nitrogen efficient cultivars without sacrificing rice yield potential, improving grain fill in later-flowering inferior spikelets and enhancing harvest index are three important approaches to achieving the dual goal of high grain yield and high resource use efficiency. Deeper root distribution and higher leaf photosynthetic N use efficiency at lower N rates could be used as selection criteria to develop N-efficient cultivars. Enhancing sink activity through increasing sugar-spikelet ratio at the heading time and enhancing the conversion efficiency from sucrose to starch though increasing the ratio of abscisic acid to ethylene in grains during grain fill could effectively improve grain fill in inferior spikelets. Several practices, such as post-anthesis controlled soil drying, an alternate wetting and moderate soil drying regime during the whole growing season, and non-flooded straw mulching cultivation, could substantially increase grain yield and water use efficiency, mainly via enhanced remobilization of stored carbon from vegetative tissues to grains and improved harvest index. Further research is needed to understand synergistic interaction between water and N on crop and soil and the mechanism underlying high resource use efficiency in high-yielding rice.

关键词： rice     nitrogen-efficient cultivar     grain fill     harvest index     nitrogen use efficiency     water use efficiency    

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标题 作者 时间 类型 操作

Antimicrobial use in food animal production: situation analysis and contributing factors

Ziping WU

期刊论文

Discovery of novel ursolic acid derivatives as effective antimicrobial agents through a ROS-mediated

期刊论文

of copper nanoparticles on multiwalled carbon nanotubes modified with poly (acrylic acid) and their antimicrobial

Li SHENG,Shuhang HUANG,Minghao SUI,Lingdian ZHANG,Lei SHE,Yong CHEN

期刊论文

Review on drivers, trends and emerging issues of the food wastage in China

Lin MA,Wei QIN,Tara GARNETT,Fusuo ZHANG

期刊论文

Microwave-assisted synthesis and antimicrobial activities of 2-aryl-3-(naphthalene-1 or 2-yl)-1,3-thiazolidin

Hua CHEN, Yanan LI, Jie BAI, Lian ZHAO, Xiangguo YUAN, Xiaoliu LI, Keqiang CAO

期刊论文

Antimicrobial activity of topical agents against Propionibacterium acnes: an in vitro study of clinical

null

期刊论文

Decomposing drivers of transportation energy consumption and carbon dioxide emissions for the Philippines

Neil Stephen LOPEZ, Anthony S.F. CHIU, Jose Bienvenido Manuel BIONA

期刊论文

What drivers will influence biomass allocation

Jinguang HU, William James CADHAM, Susan van DYK, Jack N. SADDLER

期刊论文

越南广平和顺化两省猪场分离副猪嗜血杆菌的抗生素耐药表型和耐药基因之间的相关性研究

Chao Nguyen Van, 张丽君, Tam Vu Thi Thanh, Hung Pham Hoang Son, Tuan Tran Ngoc, 黄琦, 周锐

期刊论文

Moving policy and regulation forward for single-use plastic alternatives

期刊论文

吖啶– 核定位序列偶联构建的高活性抗菌肽

Wei Zhang,Xiaoli Yang,Jingjing Song,Xin Zheng,Jianbo Chen,Panpan Ma,Bangzhi Zhang,Rui Wang

期刊论文

细菌耐药性威胁人类健康

沈建忠, Timothy R. Walsh

期刊论文

Nudging sustainable consumption of residential energy use: A behavioral economics perspective

期刊论文

Drivers and barriers to engage enterprises in environmental management initiatives in Suzhou Industrial

Bing ZHANG, Jun BI, Beibei LIU

期刊论文

Approaches to achieve high grain yield and high resource use efficiency in rice

Jianchang YANG

期刊论文